End-Stage Alcoholism End-stage alcoholism represents the final and most severe phase of alcohol use disorder, characterized by extensive physical and psychological damage due to chronic alcohol consumption. Individuals at this stage often exhibit severe liver dysfunction, leading to complications and hepatic encephalopathy, which can cause confusion, disorientation, and even coma. Additionally, they may experience significant malnutrition and vitamin deficiencies, particularly thiamine deficiency, which can result in serious neurological disorders. https://gorehabs.com/blog/end-stage-alcoholism-sign-symptoms-and-treatment/